作为国家综合立体交通网的重要组成部分，以高速公路、高速铁路、民用航空组成的快速综合交通网能够显著优化资源配置、促进创新要素流动、降低客货运输成本。为探究快速综合交通网与区域创新发展之间的耦合协调机制，选取山东省16个地级市为研究对象，以2013年、2015年、2017年、2020年为时间横断面，构建快速综合交通网优势度与区域创新能力两个子系统评价指标体系，利用熵权TOPSIS法和耦合协调模型研究两者时空分布格局及耦合协调演化特性。结果表明：①快速综合交通网优势度、区域创新能力两个子系统之间的耦合协调水平呈现出稳中有升的发展态势，快速综合交通网优势度与区域创新能力之间存在正相关关系，“高速公路+高速铁路+航空运输”多式联运地区的创新水平最高；②快速综合交通网优势度与区域创新能力均以省内经济圈核心城市为中心向外圈层递减，呈现向经济圈中核心城市集聚的特征；③快速综合交通网与区域创新的耦合存在空间差异性，“快速综合交通优势区-区域创新优势区”大多处于基础设施完备的交通枢纽、交通干线和经济贸易繁荣地区，且呈高度优质耦合协调的空间特征；而创新能力低、远离交通枢纽和主要交通干线的“快速综合交通弱势区-区域创新弱势区”处于交通末梢外围边缘区，且快速综合交通网建设对区域创新发展存在马太效应。

As an important part of the national comprehensive three-dimensional transportation network, the rapid integrated transportation network consisting of expressway, high-speed railway and civil aviation can significantly optimize the allocation of resources, promote the flow of innovation factors and reduce the cost of passenger and cargo transportation. In order to investigate the coupling and coordination mechanism between rapid integrated transport network and regional innovation development, this paper selected 16 cities in Shandong Province as research objects, chose 2013, 2015, 2017 and 2020 as time transects, and constructed two sub-system evaluation index systems, namely rapid transport network superiority and regional innovation capacity. It used entropy weight TOPSIS method and coupling coordination model to study the spatial and temporal distribution patterns and the evolution coupling and coordination characteristics of them. The research results are as follows: ①The level of coupling and coordination between rapid integrated transport network superiority and regional innovation capacity, shows a stable and increasing development trend. There is a positive relationship between rapid integrated transport network superiority and regional innovation, with the highest innovation intensity in the "expressway, high-speed railway and air transport" multimodal transport area. ②The rapid integrated transport network superiority and regional innovation capacity both show a decreasing trend from the core city of the provincial economic circle to the outer circle, presenting the characteristics of clustering in core cities within the economic circle. ③There are spatial differences in the coupling between the rapid integrated transport network and regional innovation. Most of the "rapid integrated transport advantaged areas-regional innovation advantaged areas" are located in transport hubs, transport arteries and prosperous economic and trade areas with complete infrastructure, and showing high quality coupling and coordinated spatial characteristics. However, the "rapid integrated transport disadvantaged-regional innovation disadvantaged" areas with low innovation capacity and far from transport hubs and main transportation arteries are located at the periphery of the transport terminal, and the construction of the rapid integrated transport network has a Matthew's effect on regional innovation development.